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DeCS
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Descriptor English:
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Pharmacogenomic Variants
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Descriptor Spanish:
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Variantes Farmacogenómicas
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Descriptor Portuguese:
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Variantes Farmacogenômicos
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Synonyms English:
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Pharmacogenetic Variants
Pharmacokinetic Genetic Variants
Genetic Variant, Pharmacokinetic
Genetic Variants, Pharmacokinetic
Pharmacogenetic Variant
Pharmacogenomic Variant
Pharmacokinetic Genetic Variant
Variant, Pharmacogenetic
Variant, Pharmacogenomic
Variants, Pharmacogenetic
Variants, Pharmacogenomic
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Tree Number:
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G05.365.795.446
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Definition English:
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Naturally occurring genetic variations associated with drug response (e.g., dosage, extent and rate of metabolic processes). While these variants are not markers for GENETIC PREDISPOSITION TO DISEASE they influence PHARMACOKINETICS and pharmacodynamics and often occur on genes encoding drug metabolism enzymes and transporters (e.g., ANGIOTENSIN CONVERTING ENZYME; CYTOCHROME P-450 CYP2D6). |
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See Related English:
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Pharmacogenetics
Precision Medicine
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56761
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Unique Identifier:
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D000071184
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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